Rapid presumptive bacteriological diagnosis of Legionnaires disease

Rapid diagnosis of Legionnaires' disease by bronchoalveolar lavage.

Legionella pneumophila has, in recent years, emerged as a common pulmonary pathogen in the normal and immuno-compromised patient (ICP). Making a specific etiologic diagnosis of pneumonia in the latter group is a common clinical dilemma often complicated by poor specimen availability and risks of invasive procedures. Improved staining and isolation techniques for L pneumophila would suggest that...

The diagnosis of Legionnaires' disease by counterimmunoelectrophoresis.

Counterimmunoelectrophoresis (CIE) was found to be a rapid, specific method for detecting circulating antibodies to Legionella pneumophila, the aetiologic agent of Legionnaires' disease in human sera. Optimum conditions for performing the test are given. Better precipitin lines are observed when the gel support is neutral, and a result may be obtained in 90 to 180 minutes. Comparison of results...

New Approaches for the Laboratory Diagnosis of Legionnaires’ Disease

The key role of diagnostic tests in clinical microbiology is the accurate and timely detection of an etiologic agent(s) causing infection to enable clinicians to provide the most effective therapy in an early stage. Unfortunately, the ideal test for Legionella spp. does not exist. Although diagnostic methods have improved during the 30 years since L. pneumophila was first described, no currentl...

The diagnosis of Legionnaires ' disease by counterimmunoelectrophoresis MALCOLM

Counterimmunoelectrophoresis (CIE) was found to be a rapid, specific method for detecting circulating antibodies to Legionella pneumophila, the aetiologic agent of Legionnaires' disease in human sera. Optimum conditions for performing the test are given. Better precipitin lines are observed when the gel support is neutral, and a result may be obtained in 90 to 180 minutes. Comparison of results...

Clinical Diagnosis: The Bacteriological, Chemical, and Microscopical Evidence of Disease